Stomach (gastric) ulcers hauv dev tshwm sim thaum lub plab tiv thaiv kab mob, hu ua mucosal barrier, ua puas. Lub hom phiaj ntawm lub mucosal barrier yog los tiv thaiv lub plab ntawm lub plab los ntawm nws cov acidic txheem.
Lub zog ntawm mucosal barrier nyob ntawm ntau yam:
- Lub cev Cheebtsam (piv txwv li, mucus)
- ntshav txaus rau lub plab zom mov (GI) kab mob
- Muaj peev xwm ntawm cov hlwb hauv plab kom kho lossis hloov raws li xav tau
- Cov cim tshuaj (piv txwv li, prostaglandins) tswj cov hnoos qeev, ntshav khiav, thiab kev loj hlob ntawm tes
Txhua yam uas ua rau lub plab acid ntau ntxiv lossis hloov cov mucosal barrier tuaj yeem ua rau mob plab uas, ib zaug tam sim no, feem ntau yuav hnyav dua yam tsis tau kho. Qhov no yog vim ib qho kev hloov feem ntau spirals mus rau hauv ib qho kev puas tsuaj ntxiv.
Dab tsi ua rau plab plab hauv dev?
Cov kab mob plab tsis yog tshwm sim ib txwm muaj, tshwj xeeb tshaj yog cov menyuam yaus noj qab nyob zoo. Ib txoj kev tshawb fawb pom tias feem ntau ua rau mob plab hauv cov dev ua kab mob siab thiab cov tshuaj uas tsis yog tshuaj steroidal anti-inflammatory (NSAID). Txawm li cas los xij, ntau yam sib txawv tuaj yeem ua rau muaj mob plab.
1. Tshuaj
Non-steroidal anti-inflammatory tshuaj (NSAIDs) yog cov culprits ntau, nrog rau tib neeg cov khoom (xws li, aspirin, ibuprofen) thiab veterinary khoom (xws li, meloxicam). Corticosteroids (piv txwv li, prednisone, dexamethasone) kuj tau cuam tshuam.
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias corticosteroids thiab NSAIDs (los yog ntau NSAIDs) yuav tsum tsis txhob muab ua ke, vim qhov no ua rau muaj kev pheej hmoo ntawm mob plab.
Ib lub sij hawm "ntxuav" feem ntau pom zoo yog tias tus neeg mob yuav tsum tau hloov ntawm ib hom tshuaj mus rau lwm qhov, thiab cov tshuaj tiv thaiv plab yuav tau txais kev txhawb nqa.
2. Qee yam Kev Kho Mob
Cov kab mob plab feem ntau tshwm sim hauv cov dev uas muaj kab mob siab thiab mob raum. Lwm yam mob xws li mob pancreatitis, chim siab plob tsis so tswj (IBS), thiab cov kab mob tseem ceeb (piv txwv li, sepsis) kuj tau cuam tshuam nrog mob plab.
3. Txo cov ntshav ntws mus rau plab
Cov ntshav ntws mus rau lub plab tuaj yeem txo qis hauv cov xwm txheej hnyav xws li tshuaj loog, hypovolemic shock, thiab gastric dilatation-volvulus (GDV). Nws kuj tseem tuaj yeem tshwm sim hauv qee cov kab mob ntev, piv txwv li hypoadrenocorticism (Addison's Disease).
4. Dietary Indiscretion
Aub uas noj tej yam uas lawv yuav tsum tsis txhob (xws li, lub cev khoom los yog tshuaj lom) tuaj yeem ua rau lub qhov ncauj qhov ntswg ncaj qha.
5. Hyperthermia (Heat Stroke)
plab ulcers yog tshwm sim nyob rau hauv hnyav mob stroke.
6. Exercise-induced Gastric Disease (EIGD)
EIGD tau raug sau tseg hauv cov neeg ncaws pob qib siab uas ua rau lub cev xav tau kev ua ub no, tshwj xeeb tshaj yog kev sib tw ncaws pob sled dev.
7. Neoplasia (Cancer)
Cancer tuaj yeem ua rau mob plab hauv ob txoj kev:
- Cov qog uas cuam tshuam ncaj qha rau lub plab (tsis muaj nyob rau hauv cov dev, tab sis ib qho piv txwv yog leiomyosarcoma).
- Paraneoplastic syndrome, qhov chaw mob qog noj ntshav hauv lwm qhov ntawm lub cev ua rau muaj kev hloov pauv hauv mucosal barrier. Ib hom mob qog noj ntshav uas feem ntau cuam tshuam yog cov qog nqaij hlav mast cell (MCTs).
8. Spinal Cord Injury
Tauma rau tus txha caj qaum, suav nrog tus kab mob intervertebral disc (IVDD), tau cuam tshuam nrog mob plab hauv dev.
Cov tsos mob ntawm plab hnyuv hauv dev yog dab tsi?
Cov tsos mob ntawm plab rwj feem ntau tsis meej heev, thiab qee tus dev yuav tsis pom cov tsos mob hlo li.
Txoj kev mus saib suav nrog:
- Kev tshaib plab
- Nausea (doo dej ntau dhau, tig taub hau tawm ntawm zaub mov)
- ntuav (cov khoom ntuav tuaj yeem los yog tsis muaj ntshav, uas yuav zoo li liab liab lossis muaj xim av xim "xim av" zoo li)
- Pab mob plab
- poob phaus, yog hais tias lub qhov txhab tau tshwm sim ib ntus
Qee zaum, qhov txhab tuaj yeem nce mus rau qhov perforation (qhov) hauv plab. Qhov no warrants ceev veterinary saib!
Afected dogs may:
- Zoo qaug zog los yog qaug zog dheev
- Muaj cov pos daj daj thiab daim di ncauj
- Qhia mob plab
Hmoov tsis zoo, cov dev uas muaj kab mob plab perforated muaj kev tiv thaiv kab mob.
Pab mob plab mob li cas?
Koj tus kws kho tsiaj tej zaum yuav xav tias mob plab yog tias koj tus dev muaj ib los yog ntau tshaj qhov ua rau pom thiab pom cov cim qhia saum toj no. Lawv yuav kuaj xyuas lub cev kom zoo, yuav ua rau ntshav, thiab lwm yam kev kuaj mob kom txiav txim siab lwm yam ua rau mob plab. Yog tias tsis muaj kev txhawj xeeb pom tseeb, kev sim tshuaj tua kab mob tuaj yeem raug qhia kom pom seb koj tus dev cov tsos mob zoo li cas.
Kom paub meej tias mob plab rwj, kev kuaj mob endoscopic yuav raug pom zoo. Qhov no suav nrog cov tshuaj loog dav dav kom lub koob yees duab me me tuaj yeem dhau los ntawm qhov ncauj, tshuaj esophagus, thiab lub plab kom saib cov pov thawj los ntshav thiab / lossis mob. Yog tias muaj qhov txawv txav tau raug txheeb xyuas, cov qauv kuaj (biopsies) ntawm thaj chaw cuam tshuam tuaj yeem raug coj los txiav txim seb qhov twg tshwm sim.
Qee zaum, kev tshawb nrhiav kev phais yuav pab tau. Cov paib cuam tshuam nrog mob plab zoo ib yam li ntau lwm yam ua rau mob plab hnyuv (GI) chim siab. Thaum kev phais mob ntau dua li kev kuaj mob endoscopy, nws muab lub sijhawm los tshuaj xyuas tag nrho cov kab mob GI thiab lwm yam kabmob plab. Nws kuj tso cai rau biopsies.
Pab mob plab mob li cas hauv dev?
Ntau npaum li qhov ua tau, cov kev kho mob uas yuav ua rau kev loj hlob ntawm plab rwj yuav tsum tau tswj. Qee tus neeg mob yuav xav tau mus pw hauv tsev kho mob rau cov kua dej tso (IV) thiab lwm yam kev pab txhawb nqa.
Luv luv, ntawm no yog cov tshuaj uas nquag siv los kho mob plab. Lawv yog tib neeg cov tshuaj, tam sim no siv off-label nyob rau hauv dev:
1. Proton-pump Inhibitors (piv txwv li, omeprazole)
Cov tshuaj no zoo heev txo cov kua qaub hauv plab.
2. Histamine-2 Receptor Antagonists (piv txwv li, famotidine)
Cov no kuj txo qis cov kua qaub hauv plab, tab sis tsis zoo li proton-pump inhibitors.
3. Prostaglandin Analogues (piv txwv li, misoprostol)
Misoprostol inhibits plab acid ntau lawm thiab muaj kev tiv thaiv zoo rau cov hlwb hauv cov kab mob GI. Cov poj niam cev xeeb tub yuav tsum tsis txhob noj cov tshuaj no, vim nws yuav ua rau nchuav menyuam.
4. Cytoprotective Agents (piv txwv li, sucralfate)
Sucralfate khi rau qhov chaw puas hauv plab, tiv thaiv cov hlwb los ntawm kev puas tsuaj ntxiv. Nws kuj ua rau cov hnoos qeev ntau ntxiv. Vim nws lub plab txheej txheej, nws tuaj yeem thaiv kev nqus ntawm lwm yam tshuaj. Sucralfate yuav tsum tau muab tsawg kawg 1-2 teev sib nrug ntawm zaub mov thiab lwm yam tshuaj.
Nws tsim nyog sau cia tias cov neeg mob uas tau txais cov tshuaj proton-twj inhibitors lossis histamine-2 receptor antagonists ntev tshaj li ib hlis yuav tsum tau txiav tawm cov tshuaj maj mam kom tsis txhob muaj qhov cuam tshuam rov qab los ntawm kev tsim cov kua qaub hauv plab.
Lub plab ulcers yuav siv sij hawm ntev npaum li cas?
Lub sijhawm kho mob plab yog qhov sib txawv heev. Nws nyob ntawm qhov hnyav ntawm qhov txhab, thiab seb puas muaj cov hauv paus ntsiab lus (piv txwv li, kab mob siab lossis raum) uas yuav ua rau muaj kev loj hlob ntawm ulcer.
Puas Tshav plab plab tuaj yeem tiv thaiv tau?
Txawm hais tias tsis yog txhua qhov mob plab tuaj yeem tiv thaiv tau, muaj qee yam koj tuaj yeem ua kom txo tau koj tus dev txoj kev pheej hmoo:
- Tsis txhob muab koj tus dev noj tshuaj tom khw (piv txwv li, tshuaj aspirin) yam tsis tau sab laj nrog kws kho tsiaj
- Thaum muab tshuaj rau koj tus dev, xws li NSAID mus sij hawm ntev, siv cov tshuaj qis tshaj plaws uas ua rau lawv xis nyob (ntau txoj hauv kev los tswj qhov mob tuaj yeem pab txo qis qhov xav tau)
- Tsis txhob muab corticosteroids thiab NSAIDs ua ke
- Tsis txhob cia koj tus dev zom txhua yam uas tuaj yeem ua rau tawg tawg thiab nqos tau
- Khaws cov nroj tsuag hauv tsev, khib nyiab, thiab lwm yam tshuaj lom neeg kom nyab xeeb ntawm koj tus dev mus txog
- Saib xyuas kom tsis txhob muaj cua sov, thiab sab laj nrog koj tus kws kho tsiaj kom cov lus qhia yog tias koj tus dev tsis tu ncua koom nrog kev ua ub ua no strenuous
- Nrog koj tus kws kho tsiaj cov kev pab, tswj txhua yam kev mob uas koj tus dev muaj uas yuav ua rau muaj mob plab
Yog tias koj muaj kev txhawj xeeb txog koj tus dev lub peev xwm los tsim cov kab mob, lossis yog tias koj txhawj xeeb tias lawv yuav mob plab, thov hu rau koj tus kws kho tsiaj kom pab.
